genetic mutation

noun

plural genetic mutations
: a permanent alteration in the nucleotide sequence of one or more genes or in the number or structure of one or more chromosomes
Lacking working copies of the p53 gene, cells can begin to divide without check, though several other genetic mutations are thought to be needed to foster a full-blown malignancy.Natalie Angier

Examples of genetic mutation in a Sentence

Recent Examples on the Web
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Its hue is the result of a very rare genetic mutation. Laura Baisas, Popular Science, 25 Dec. 2024 Werewolf Cat This cat, the result of a genetic mutation, looks more like a haggard, partially hairless feline than a wolf-like creature, as its name would suggest. Paul Smaglik, Discover Magazine, 22 Oct. 2024 Plus, some genetic mutations make people respond better to certain treatments, Dr. Adesoye says. Wendy Grossman Kantor, People.com, 10 Oct. 2024 Jahangir will be wearing portable health data collection devices so Vanderbilt researchers might look at how space affects the immune system, genetic expression and genetic mutations in blood stem cells. Brad Schmitt, The Tennessean, 28 Aug. 2024 See all Example Sentences for genetic mutation 

Word History

First Known Use

1915, in the meaning defined above

Time Traveler
The first known use of genetic mutation was in 1915

Dictionary Entries Near genetic mutation

Cite this Entry

“Genetic mutation.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genetic%20mutation. Accessed 18 Jan. 2025.

Medical Definition

genetic mutation

noun
: a permanent alteration in the nucleotide sequence of one or more genes or in the number or structure of one or more chromosomes
Gaucher's disease results from one of many genetic mutations that can either slow or prevent the breakdown of certain glycolipids, which accumulate in storage vesicles and eventually kill cells.Joseph Alper
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